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News outlets: Our latest study on the role of quorum sensing in hair plucking induced regeneration was covered by
Scienctific American
BBC News
Smithsonian magazine

The birth of birds was selected as one of the top10 scientific achievements of 2014

A concept animal showing ectodermal and endodermal organs

Research Description
    The laboratory asks fundamental questions in bio-medical research. The focus of our research is morphogenesis, i.e. how cells are assembled into functional forms. We are concerned with the principles that determine the specific number, size and shape of different organs. This is an important process, as there is much to learn about the principles that can guide stem cells to form specific tissues and organs required for medical treatment. Our approach is to ask Nature how she does it - using the feather as a Rosetta stone to decipher these principles, because of the distinctive forms of feathers and interest in the evolution of flight. This unique model has allowed us to make several major impacts in the field of morphogenesis and develop interesting interfaces with scientists in different disciplines.  

Plucking induced hair regeneration

Organ-level quorum sensing directs regeneration in hair stem cell populations

Cell 161:277-290, 2015

High magnification view of regenerative response to plucking involves the regeneration of all follicles (the 200 plucked and 600 unplucked) within the plucked area (dotted red circle) followed by regeneration of unplucked follicles (400 HFs in total) outside the boundaries of the plucked area due to hair wave propagation (dotted blue circle).

@Cheng-Ming Chuong
July 2017