Articles
2011
Plikus MV, Baker RE, Chen CC, Fare C, de la Cruz D, Andl T, Maini PK, Millar SE, Widelitz R, Chuong CM. Self-organizing and stochastic behaviors during the regeneration of hair stem cells. Science 332:586-589, 2011. Supporting On-line Materials Movie 1 Movie 2 Movie 3 Movie 4 Movie 5 Movie 6 Movie 7 Movie 8 Movie 9
Jiang TX, Tuan TL, Wu P, Widelitz RB, Chuong CM. From buds to follicles: Matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis. Differentiation. 2011.
Hughes MW, Wu P, Jiang TX, Lin SJ, Dong CY, Li A, Hsieh FJ, Widelitz RB, Chuong CM. In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages. Integr Biol (Camb). 3:388-407, 2011.
Lee LF, Jiang TX, Garner W, Chuong CM. A simplified procedure to reconstitute hair-producing skin Tiss Eng Part C 17:1-10, 2011.
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2010
Al-Nuaimi Y, Baier G, Watson RE, Chuong CM, Paus R. The cycling hair follicle as an ideal systems biology research model.Exp Dermatol. 19:707-713, 2010.
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2009
Yeh J, Green LM, Jiang TX, Plikus M, Huang E, Chang RN, Hughes MW, Chuong CM, Tuan TL.Accelerated closure of skin wounds in mice deficient in the homeobox gene Msx2.Wound Repair Regen. 17:639-648, 2009.
Lin CM, Jiang TX, Baker RE, Maini PK, Widelitz RB, Chuong CM. Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation. Dev. Biol. 334:369-382, 2009.
Rubenstein M, Sai Y, Chuong CM, Shen WM. Regenerative patterning in Swarm Robots: mutual benefits of research in robotics and stem cell biology. Int J Dev Biol. 53:869-881, 2009.
Richardson, MK and Chuong, C-M. Regeneration and pattern formation - an interview with Susan Bryant. Int J Dev Biol. 53:827-833, 2009.
Chang C, Wu P, Baker RE, Maini PK, Alibardi L, Chuong CM. Reptile scale paradigm: Evo-Devo, pattern formation and regeneration. Int J Dev Biol. 53:813-26, 2009.
Chuong CM, Widelitz RB. The river of stem cells. Cell Stem Cell. 4:100-102, 2009.
Lee LF, Chuong CM. Building complex tissues: high-throughput screening for molecules required in hair engineering. Invest Dermatol, 129:815-7, 2009
Plikus MV, Widelitz RB, Maxson R, Chuong CM. Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity. Int J Dev Biol. 2009.
Li, MY. The master of chicken feather and duck bill research: Cheng-Ming Chuong. Sci. Am. (Chinese version) 84:114-119, 2009.
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2008
Plikus MV, Mayer JA, de la Cruz D, Baker RE, Maini PK, Maxson R, Chuong CM. Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature, 451:340-4, 2008.
Mayer JA, Foley J, De La Cruz D, Chuong CM, Widelitz R. Conversion of the nipple to hair-bearing epithelia by lowering bone morphogenetic protein pathway activity at the dermal-epidermal interface. Am J Pathol. 173:1339-48, 2008.
Plikus MV, Chuong CM. Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents. J Invest Dermatol 128:1071-80, 2008.
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2007
Widelitz RB, Veltmaat JM, Mayer JA, Foley J, Chuong CM. Mammary glands and feathers: comparing two skin appendages which help define novel classes during vertebrate evolution. Semin Cell Dev Biol. 18:255-66, 2007.
Chuong CM. Regenerative biology: new hair from healing wounds. Nature. 447:265-266, 2007.
Wang XP, Suomalainen M, Felszeghy S, Zelarayan LC, Alonso MT, Plikus MV, Maas RL, Chuong CM, Schimmang T, Thesleff I. An integrated gene regulatory network controls stem cell proliferation in teeth. PLoS Biol.5:e159, 2007.
Drew FC, Lin CM, Jiang TX, Blunt G, Mou C, Chuong CM, Headon DJ. The Edar subfamily in feather placode formation. Developmental Biology 305:232-45, 2007.
Chuong CM, Cotsarelis G, Stenn K. Defining hair follicles in the age of stem cell bioengineering. J Invest Dermatol, 127:2098-100, 2007.
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2006
Yue Z, Jiang TX, Widelitz RB, Chuong CM. Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia. Proc Natl Acad Sci U S A. 103:951-5, 2006.
Wu P, Jiang TX, Shen JY, Widelitz RB, Chuong CM. Morphoregulation of avian beaks: comparative mapping of growth zone activities and morphological evolution. Dev. Dyn. 235:1400-12, 2006.
Chuong CM, Dhouailly D, Gilmore S, Forest L, Shelley WB, Stenn KS, Maini P, Michon F, Parimoo S, Cadau S, Demongeot J, Zheng Y, Paus R, Happle R. What is the biological basis of pattern formation of skin lesions? Exp Dermatol. 15:547-64, 2006.
Widelitz RB, Baker RE, Plikus M, Lin CM, Maini PK, Paus R, Chuong CM. Distinct mechanisms underlie pattern formation in the skin and skin appendages. Birth Defects Res C Embryo Today. 78:280-91, 2006.
Plikus MV, Zhang Z, Chuong CM. PubFocus: semantic MEDLINE/PubMed citations analytics through integration of controlled biomedical dictionaries and ranking algorithm. BMC Bioinformatics. 2;7:424, 2006.
Plikus, MV, Sundberg, JP and Chuong, CM. Mouse Skin Ectodermal Organs. In The Mouse in Biomedical Research, Academic Press. NY. Volume III Normative Biology, Husbandry, and Models. 2006.
Lin CM, Jiang TX, Widelitz RB, Chuong CM. Molecular signaling in feather morphogenesis. Curr Opin Cell Biol. 18:730-41, 2006.
Maini PK, Baker RE, Chuong CM. Developmental biology. The Turing model comes of molecular age. Science. 314:1397-8, 2006.
Chuong, C-M., Wu, P., Plikus MV, Jiang, TX, Widelitz, RB. Engineering Stem cells into organs: Topobiological transformations demonstrated by beak, feather and other ectodermal organ morphogenesis. Current Topics in Developmental Biology. 237-74, 2006.
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2005
Yue ZC, Jiang TX, Widelitz RB, Chuong CM. Mapping Stem Cell Activities in the Feather Follicle. Nature 438:1026-1029, 2005.
Plikus, MV., Zeichner-David, M., Mayer, J.A., Reyna, J., Bringas, P., Thewissen, J. G. M., Snead, ML., Chai, Y.,Chuong, CM "Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity". Evolution and Development. 7:440–457, 2005.
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2004
Hou, L., Chiappe, L.M., Zhang, F., and Chuong, C-M. New Early Cretaceous fossil from China documents a novel trophic specialization for Mesozoic birds. Naturwissenschaften. 91: 22-25, 2004.
Suksaweang, S., Lin C-M., Jiang, T-X., Hughes, M.W., Widelitz, R.B., and Chuong, C-M. Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation. Dev Biol. 266:109-122, 2004.
Plikus M, Wang WP, Liu J, Wang X, Jiang TX, Chuong CM. Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway. Am J Pathol. 164:1099-114, 2004.
Plikus M, Chuong CM. Making waves with hairs. J Invest Dermatol. Apr;122:vii-ix, 2004.
Chang, C.-H., Yu, M., Wu, P., Jiang, T.-X., Yu, H.-S., Widelitz, R.B., and Chuong, C.-M. Sculpting Skin Appendages Out of Epidermal Layers Via Temporally and Spatially Regulated Apoptotic Events. J. Invest. Dermato. 122: 1348-1355, 2004.
Shen, W.-M., P. Will, A. Galstyan, C.-M. Chuong, Hormone-inspired self-organization and distributed control of robotic swarms. Autonomous Robots, 17, 93-105, 2004.
Wu, P. Hou, L. Plikus, M, Hughes, M., Scehnet, J., Suksaweang, S., Wideltz, RW., Chuong, CM. Evo-Devo of amniote integuments and appendages. Int. J. Developmental Biol. 48:249-270, 2004.
Jiang, T-X., Wideltz, RB., Shen, WM., Will, P., Wu, DY., Lin, CM., Jung, JS., Chuong, CM. Integument pattern formation involves genetic and epigenetic controls operated at different levels: Feather arrays simulated by a digital hormone model. Int. J. Developmental Biol. 48:117-136, 2004.
Yu, M., Yue, Z., Wu, P., Wu, D.-Y., Mayer, J.A., Medina, M., Widelitz, R.B., Jiang, T.-X., and Chuong, C.-M. The developmental biology of feather follicles. Int. J. Developmental Biol. 48:181-191, 2004.
Wu, P., Jiang, T.-X., Suksaweang, S, Wideltz, RB., Chuong, CM. Molecular Shaping of the Beak. Science, 305:1465-1466, 2004. Supplement
Mayer, JA., Chuong, CM., Widelitz, R. Rooster feathering, androgenic alopecia, and hormone dependent tumor growth: What is in common? Differentiation. 72: 474-488, 2004.
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2003
Chodankar R., Chang C-H, Yue Z., Suksaweang S., Burrus L., Chuong C-M, and Widelitz RB. Shift of Localized Growth Zones Contributes to Skin Appendage Morphogenesis: Role of the Wnt/Beta-catenin Pathway. J Inv Dermatol. 120:19-26, 2003.
Chuong, C-M. Homeobox Genes, Fetal Wound Healing, and Skin Regional Specificty. J Invest Dermatol. 120:9-11, 2003.
Chuong, C-M and Homberger, D.G. Development and Evolution of the Amniote Integument: Current Landscape and Future Horizon. J Exp Zool. 298B: 1-11, 2003.
Chuong, C-M, Wu, P., Zhang, F-C, Xu, X., Yu, M., Widelitz, R.B., Jiang, T-X, and Hou, L. Adaptation to the Sky: Defining the Feather With Integument Fossils From Mesozoic China and Experimental Evidence From Molecular Laboratories. J Exp. Zool. 298B: 42-56, 2003.
Widelitz, R.B., Jiang, T-X, Yu, M., Shen, T., Shen, J-Y, Wu, P., Yu, Z., and Chuong, C-M. Molecular Biology of Feather Morphogenesis: A Testable Model for Evo-Devo Research. J Exp Zool. 298B: 109-122, 2003.
Hughes, M.W., and Chuong, C-M. A Mouthful of Epithelial-Mesenchymal Interactions. J Invest Dermatol. 121:vii-viii, 2003.
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2002
Chuong C-M. Development, Tissue Engineering, and Cancer: Guidance of Stem Cells. Changhua J Med. 7: 1-7, 2002.
Koh S., Li H., Lee Y-H, Widelitz R.B., Chuong C-M., and Stallcup M.R. Synergistic Coactivator Function by Coactivator-associated Arginine Methyltrasferase (CARM) 1 and Beta-Catenin with Two Different Classes of DNA-binding Transcriptional Activators. J. Biol. Chem. 277: 26031-26035, 2002.
Chuong C-M, Nickloff BJ, Elias PM, Goldsmith LA, Macher E., Maderson PA., Sundberg JP., Tagami H., Plongka PM., Thestrup-Pedersen K., Bernard BA., Scroder JM., Dotto P., Chang C-H., Williams ML., Feingold KR., King LE., Kligman AM., Rees JL., Christophers E. What is the ‘true’ function of skin. Exp. Dermatol. 11:159-87, 2002.
Ma L., Liu J., Wu T., Plikus M., Jiang T.-X, Liu Y-H, Muller-Rover S., Brissette J., Peters H., Maxson R., Maas R., and Chuong C-M. Cyclic alopecia in Msx2 mutants: Defects in hair cycling and hair shaft differentiation. Development and Disease. 130:379-389, 2002.
Shen, W-M, and Chuong, C-M. Simulating Self-Organization with the Digital Hormone Model. Multi-Robot Systems: From Swarms to Intelligent Automata., (A. Schultz and L. Parker, eds.), Kluwer Academic Publishers, 2002.
Shen, W-M, Chuong, C-M, and Will, P. Digital Hormone Models For Self-Organization. International Conference on Simulation and Synthesis of Living Systems. Sydney Australia, 2002.
Shen, W-M, Chuong, C-M, and Will, P. Simulating Self-Organization for Multi-Robot Systems. International Conference on Intelligent and Robotic Systems. Switzerland, 2002.
Yu M, Wu P, Widelitz RB, and Chuong C-M. The Morphogenesis of feathers. Nature. 420:308-312, 2002.
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2001
Lin, S-L, Chuong,C-M, and Ying, S-Y. A Novel mRNA-cDNA Interference Phenomenon for Silencing bcl-2 Expression in Human LNCaP Cells" Biochem. Biophysi. Res. Comm. 281:639-644, 2001.
Lin S-L and Ying S-Y. DRNAi (Messenger RNA-antisense DNA Interference) as a Novel Defense System Against Cancer and Viral Infections. Current Cancer Drugs Targets. 1:241-247, 2001.
Chuong, C-M, Hou, L.H., Chen, PJ, Wu, P., Patel, N, and Chen, YP. Dinosaur’s feather and Chicken’s tooth? Tissue engineering of the integument. John Ebbling lecture. Eur. J. Dermatology. 11:286-292, 2001.
Hsu Y.-H, Shaw C.-K, Chuong CM. Immunohistochemical localization of deleted-in-colon-cancer (DCC) protein in human epithelial, neural, and neuro-endocrine tissues in paraffin sections with antigen retrieval. Kaohsiung J Med Sci 17:351-357, 2001 (Abstract).
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2000
Chuong, C.-M. Skin Morphogenesis: Embryonic chicken skin explant cultures. In Tuan and Lo edit: Developmental Biology Protocols. Vol. 2. In Methods in Molecular Biology Series,. Humana Press Inc. Totowa, NJ. Pp. 101-106, 2000.
Stott. S. and Chuong, C.-M. Application of retroviral gene transduction to limb bud micromass cultures. In Tuan and Lo edit: Developmental Biology Protocols. Vol. 1. In Methods in Molecular Biology Series,. Humana Press Inc. Totowa, NJ. Pp 509-513, 2000.
Widelitz, R.B., Jiang, T.-X., Lu, J.-F. and Chuong, C.-M. Beta catenin in epithelial morphogenesis: Conversion of part of avian foot scales into feather buds with a mutated beta catenin. Dev. Biol. 219:98-114, 2000.
Chen, J. and Chuong, C.-M. Dynamic expression of lunatic fringe during feather morphogenesis: a switch from medial-lateral to anterior-posterior asymmetry. Mechanism of Development. 91:351-354, 2000.
Wu, T. and Chuong, C.-M. Developmental Biology of Skin Appendages. In Camacho, F., Randall, V.A., and Price, V.H. edit Hair Biology and Disorders: Research, Pathology and Management. Martin Dunitz Pub. Pp 17-37, 2000.
Chen, Y.P., Zhang, Y., Jiang, T.X., Barlow, A., Amand, TR, Hu, Y., Heaney, S., Francis- West, P., Chuong, C.M., and Maas, R. Conservation of early odontogenic signaling pathway in Aves. Proc. Natl. Acad. Sci. 97: 10044-10049, 2000.
Chuong, C-M, Chodankar, R., Widelitz, R.B., Jiang, T. X. Evo-Devo of Feathers and Scales: Building complex epithelial appendages. Current Opinion in Development and Genetics. 10:449-456, 2000.
Chuong, C-M, Lin, J., Patel, N., Jung H-S., Widelitz, R. B. Sonic Hedgehog signaling pathway in vertebrate epithelial organ formation: Perspectives in development and evolution. Cellular and Molecular Life Sciences. 57:1672-1681, 2000.
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1999
Chuong, C.-M., Jung, H.-S. and Widelitz, R.B. Lineage and pluripotentiality of epithelial precursor cells in developing chicken skin. Biochemistry and Cell Biology 76:1069-1077, 1999.
Widelitz, R.B., Jiang, T.-X, C.-W.J., Stott, N.S. and Chuong, C.-M. Wnt-7a in feather morphogenesis: Involvement of anterior-posterior asymmetry and proximal-distal elongation demonstrated with an in vitro reconstitution model. Development. 126:2577-2587, 1999.
Jiang, T.-X., Jung, H.S., Widelitz, R.B., Chuong, C.-M. Self organization of periodic patterns by dissociated feather mesechymal cells and the regulation of size, number and spacing of primordia. Development. 126:4997-5009, 1999.
Stott, S., Jiang, T-X., and Chuong, C.-M. Successive formative stages of Precartilage mesenchymal condensations in vitro: Modulation of cell adhesion by wnt-7a and BMP-2. J. Cell Physiology. 180:314-324, 1999.
Wang, W.P.,Kasahara, N., Chuong, C.M. Update to Retroviral Gene transfer in chondrogenic limb bud micromass cultures: Adenoviral mediated gene transfer. In McClelland, M and Pardee, A. B. edit. 1999. Expression Genetics: Accelerated and High-Throughput Methods. Biotechnique Books. Eaton Publishing. Pp363-364, 1999.
Ying, S.Y., Lui, H.M., Lin. S.L., and Chuong, C.M. Generation of full length cDNA library from single human prostate cancer cells. Biotechniques. 27:410 - 414, 1999.
Lin, S.-L., Chuong, C.-M., Widelitz, R.B., Ying, S.Y. In vivo analysis of cancerous gene Expression by RNA polymerase chain reaction. Nucleic Acids Res. 27:4585-4589, 1999.
Ying, S.-Y., Chuong, C.-M., and Lin, S.-L. Suppression of activin-induced apoptosis by novel antisense strategy in human prostate cancer cells. Biochem Biphy. Res. Comm. 265:669-673, 1999.
Jiang, T.-X., Liu, Y.H., Widelitz, R.B., Kundu, R.K., Maxson, R.E. and Chuong, C.-M. Epidermal dysplasia and abnormal hair follicles in transgenic mice over-expressing homeobox gene Msx-2. J. Investigative Demato. 113:231-238, 1999.
Chuong, C.-M. and Noveen, A. Phenotypic determination of epithelial appendages: Genes, developmental pathways and evolution. J Invest Dermatol. 4:307-311, 1999.
Chen, C.-W. J. and Chuong, C.-M. Avian integument provides multiple possibilities to analyze different phases of skin appendage morphogenesis. J Invest Dermatol. 4:333-337, 1999.
Widelitz, R.B. and Chuong, C.-M. Early events in skin appendage formation: induction of epithelial placodes and condensation of dermal mesenchymal cells. J Invest Dermatol. 4:302-306, 1999.
Wang, W.-P., Widelitz, R.B., Jiang, T.-X. and Chuong, C.-M. Msx-2 and the regulation of organ size: epidermal thickness and hair length. J Invest Dermatol. 4:278-281, 1999.
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1998
Stott, S., Lee, Y.S. and Chuong, C.M. 1998. Retroviral gene transfer in micromass cultures: Potential for genetic manipulations in organotypic cultures. Biotechniques. 24:660-666.
Lee, Y.S., Stott, S., Jiang, T.-X., Widelitz, R.W. and Chuong, C.-M. 1998. Early events during precartilage condensation formation in limb bud micromass cultures: Application of retrovirus-mediated gene perturbation. Cells and Materials.8:19-32
Jung, H-S., Francis-West, F., Widelitz, R.B.,T.-X., Ting-Berreth, S., Tickle, C., Wolpert, L., and Chuong, C.-M. 1998. Local inhibitory action of BMPs and their relationships with activators in feather formation: Implications for periodic patterning. Dev. Biol. 196:11-23.
Chuong, C.-M. 1998. Feather Morphogenesis: A Model of the Formation of Epithelial Appendages. In Chuong edit, Molecular Basis of Epithelial Appendage Morphogenesis. Landes Bioscience. Austin. pp3-14.
Noveen, A., Hartenstein, V. and Chuong, C.-M. 1998. Gene networks and supernetworks: Evolutionary conserved gene interactions. In Chuong edit, Molecular Basis of Epithelial Appendage Morphogenesis. Landes Bioscience. Austin. pp371-391.
Jiang, T.-X., Stott, S., Widelitz, R. B. and Chuong, C.-M. 1998. Current methods in the study of avian skin appendages. In Chuong edit, Molecular Basis of Epithelial Appendage Morphogenesis. Landes Bioscience. Austin. pp395-408.
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1997
Lee, Y. S. and Chuong C-M. 1997. Activation of protein kinase A is a pivotal step involved in both BMP-2- and cAMP-induced chondrogenesis. J. Cell Physiol. 170:153-165.
Chen, C. J., Jung, H.-S, Jiang, T.-X. and Chuong, C.-M. 1997. Asymmetric expression of Notch, Serrate and Delta is associated with the anterior - posterior axis of feather buds. Developmental Biology. 188:181-187.
Widelitz, R. B., Jiang, T.-X., Noveen, A., Ting-Berreth, S. A., Yin, E., Jung, H-S, and Chuong, C.-M. 1997. Molecular histology in skin appendage Morphogenesis. J. Microscopy Research and Techniques. 38:452-465.
Lu, J. F., and Chuong, C.-M. Widelitz, R.W. 1997. Characterization of chicken catenin shows unique expression patterns in sites of epithelial-mesenchymal interaction. Gene. 196:201-207.
Combates, N. J., Chuong, C.-M., Stenn, K. S., and Prouty, S. M. 1997. Expression of Two Ig Family Adhesion molecules in the murine hair cycle: Enrichment of DCC in the bulge epithelia and constancy of NCAM in the follicular papilla. J. Invest. Dermatol. 109:672-678.
Stott, S. and Chuong, C.-M. 1997. Dual action of sonic hedgehog on chondrocyte hypertrophy: retrovirus mediated ectopic sonic hedgehog expression in limb bud micromass culture induces novel cartilage nodules that are positive for alkaline phosphatase and type x collagen. J. Cell Science.110:2691-2701.
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1996
Noveen, A., Jiang, T.-X., and Chuong, C.-M. 1996. cAMP, an activator of protein kinase A (PKA), suppresses the expression of sonic hedgehog. BBRC. 219:180-185.
Chuong, C.-M., Widelitz, R. W., Ting-Berreth, S. A. and Jiang, T.-X. 1996. Early Events During the Regeneration of Skin Appendages: Dependence of Epithelial-mesenchymal Interaction and Order of Molecular Reappearance. J. Investigative. Dermato. 107:639-646.
Ting-Berreth, S. A. and Chuong, C.-M.. 1996. Sonic hedgehog in feather morphogenesis: Induction of mesenchymal condensation and association with cell death. Dev. Dynamics.207:157-170.
Ting-Berreth, S. A. and C. M. Chuong. 1996. Local delivery of TGF beta2 can restore epithelium dependent organization of mesenchymal condensation during skin appendage morphogenesis. Dev. Biol. 179:347-359
Widelitz, R. B., Jiang, T.-X., Noveen, A., Chen, C.-W. J. and Chuong, C.-M. 1996. FGF induces new feather buds from developing avian skin. J. Investigative. Dermato. 107:797-803.
Chuong, C.-M. 1996. Signaling network in skin appendage induction. Second International Conference on Alopecia. International Business Communications. Southborough, MA.
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1995
Noveen, A., Jiang, T.-X. Ting-Burreth, S. A., and Chuong, C.-M. 1995. Homeobox genes Msx-1 and Msx-2 are associated with induction and growth of skin appendages. J. Invest. Dermato. 104:711-719.
Noveen, A. Jiang, T.-X. and Chuong, C.-M. 1995. Protein kinase A and protein kinase C modulators have reciprocal effects on mesenchymal condensation during skin appendage morphogenesis. Dev. Biol. 171:677-693.
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1994
Shankar, K. R., Chuong, C.-M., Jaskoll, T. and Melnick, M. 1994. Effect of in ovo retinoic acid exposure on cephalic neural crest cell migration: In vitro emigration analysis and reciprocal alteration of HNK-1 and N-CAM. Develpmental Dynamics. 200:89-102.
Chuong, C.M., Jiang, T.-X., Yin, E., Widelitz, R.B. 1994. cDCC is an epithelial cell adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction. Developmental Biology. 164:383-397.
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1993
Pacifici, M., Iwnamoto, Golden, E., Leatherman, J. L., Lee, Y.-S., Chuong, C.-M. 1994. Tenascin is involved in articular cartilage development. Developmental Dynamics, 198:123-134.
Chuong, C. M., Widelitz, R. B., Jiang, T. X., 1993. Adhesion molecules and homeoproteins in the phenotypic determination of skin appendages. J. Investigative. Dermatol. 101:10S-15S.
Widelitz, R., Jiang, T. X., Murray, B. and Chuong, C. M. 1993. Neural cell adhesion molecules (NCAM) mediate precartilaginous condensations and enhances chondrogenesis during chicken limb development. J. Cell Physiol. 156: 399-411.
Chuong, C.-M., Widelitz, R. B., Jiang, T. X., Abbott, U., Lee, Y. S. and Chen, H. M. 1993. Roles of adhesion molecules NCAM and tenascin in limb chondrogenesis. Proceedings of the 4th International Conference of Limb Development and Regeneration. pp 2165-2174. (Abstract)
Jiang, T. X., Yi, J. R., Ying, S. Y. and Chuong, C. M. 1993. Activin enhances chondrogenesis of limb bud cells: stimulation of precartilagenous mesenchymal condensations and expression of NCAM. Dev. Biol. 155:545-557.
Chuong, C.-M. 1993. The making of a feather: Homeoproteins, retinoids and adhesion molecules. BioEssays. 15:513-521.
Serras, F., Fraser, S. and Chuong, C.-M. 1993. Asymmetric patterns of gap junctional communication in developing skin demonstrated by micro-injection of Lucifer Yellow. Development. 119:85-96.
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1992
Jiang, T.-X. and Chuong, C.-M. 1992. Mechanism of feather morphogenesis: I. Analyses with antibodies to Adhesion Molecules Tenascin, N-CAM and Integrin. Dev. Biol. 150:82-98.
Chuong, C.-M., Ting, S. A., Widelitz, R. B. and Lee, Y.S. 1992. Mechanism of Skin Morphogenesis: II. Retinoic acid gradient modulates axis orientation and phenotypes of skin appendages. Development. 115:839-852.
Widelitz, R. B., and Chuong, C.-M. 1992. Replication-defective virus infection of feather buds produces a localized region of beta-galactosidase activity. Biochem. Biophysi. Res. Comm. 186:1020-1024.
Lee, Y.-L. and Chuong, C,-M. 1992. Adhesion Molecules in skeletogenesis. I. Transient expression of N-CAM in osteoblasts during endochondral and intramembranous ossification. J. Bone and Mineral Res. 7:1435-1446.
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1991
Chuong, C.-M. and Chen, H.-M. 1991. Enhanced expression of N-CAM and tenascin during wound healing. Am. J. Pathol. 138:427-440.
Chuong, C.-M., Chen, H.M., Jiang, T.X., Chia, J. 1991. Adhesion molecules in skin development: Morphogenesis of feather and hair. Ann. New York Acad. Sci. 642:263-280.
Chuong, C.-M., J. 1991. Position specific expression of homeoprotein gradients in different feather tracts. Ann. New York Acad. Sci. 642:462-464.
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1990
Chuong, C.-M. 1990a. Adhesion molecules N-CAM and tenascin in embryonic development and tissue regeneration. J. Craniofacial Genetics and Developmental Biology. 10:147 -161. (Abstract)
Chuong, C.-M. 1990b. Differential roles of multiple adhesion molecules in cell migration: Granule cell migration in cerebellum. Experientia. 46:892 - 899.
Chuong, C.-M., Oliver, G., Ting, S. Jegalian, B., Chen, H.M. and De Robertis, E.M. 1990. Gradient of homeoproteins in developing feather buds. Development 110:1021-1030.
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1982-1988
Fraser, S.E., Carhart, M.S., Murray, B.A., Chuong, C.-M., and Edelman, G.M. 1988. Alterations in the Xenopus Retinotectal Projection by Antibodies to Xenopus N-CAM. Developmental Biology 129:217-230.
Richardson, G., Crossin, K.L., Chuong, C.-M., and Edelman, G.M. 1987. Expression of cell adhesion molecules in embryonic induction: III. Development of the otic placode. Dev. Biol. 119:217-230.
Chuong, C.-M., Crossin, K.L., and Edelman, G.M. 1987. Sequential expression and differential functions of multiple adhesion molecules during the formation of cerebellar cortical layers. J. Cell Biol. 104:331-342.
Crossin, K.L., Richardson, G.P., Chuong, C.-M., and Edelman, G.M. 1987. Modulation of adhesion molecules during induction and differentiation of the auditory placode. Functions of the Auditory System., (G.M. Edelman, W.E. Gall, and W.M. Cowan, eds.), Wiley.
Daniloff, J., Chuong, C.-M., Levi, G., and Edelman, G.M. 1986. Differential distribution of cell adhesion molecules during histogenesis of the chicken nervous system. J. Neuro. Sci. 6:739-758.
Hoffman, S., Friedlander, D.R., Chuong, C.-M., Grumet, M., and Edelman, G.M. 1986. Differential contributions of Ng-CAM and N-CAM to cell adhesion in different neural regions. J. Cell Biol. 103:145-158.
Gallin, W.J., Chuong, C.-M., Finkel, L.H., and Edelman, G.M. 1986. Antibodies to L-CAM perturb inductive interactions and alter feather pattern and structure. Proc. Natl. Acad. Sci. USA 83:8235-8239.
Chuong, C.-M., and Edelman, G.M. 1985a. Expression of cell adhesion molecules in embryonic induction. I. Morphogenesis of nestling feathers. J. Cell Biol. 101:1009-1026.
Chuong, C.-M., and Edelman, G.M. 1985b. Expression of cell adhesion molecules in embryonic induction. II. Morphogenesis of nestling feathers. J. Cell Biol. 101:1027-1043.
Crossin, K.L., Chuong, C.-M., and Edelman, G.M. 1985. Expression sequences of cell adhesion molecules. Proc. Natl. Acad. Sci. USA 82:6942-6946.
Chuong, C.-M., and Edelman, G.M. 1984. Alteration in neural cell adhesion molecules during development of different regions of the nervous system. J. Neuro. Sci. 4:2354-2368.
S E Fraser, B A Murray, C M Chuong, and G M Edelman. 1984. Alteration of the retinotectal map in Xenopus by antibodies to neural cell adhesion molecules. Proc Natl Acad Sci U S A. 81:4222–4226.
Hoffman, S., Chuong, C.-M., and Edelman, G.M. 1984. Evolutionary conversation of key structures and binding functions of neural cell adhesion molecules. Proc. Natl. Acad. Sci. USA 81:6881-6885.
Grumet, M., Hoffman, S., Chuong, C.-M., and Edelman, G.M. 1984. Polypeptide components and binding functions of neuron-glia cell adhesion molecules. Proc. Natl. Acad. Sci. USA 81:7989-7993.
Chuong, C.-M. 1983. Neural cell adhesion molecules in the development of the brain. Ph.D. Thesis, The Rockefeller University, New York.
Edelman, G.M., Hoffman, S., Chuong, C.-M., Thiery, J.-P., Brackenbury, R., Gallin, W.J., Grumet, M., Greenberg, M., Hemperly, J., Cohen, C., and Cunningham, B.A. 1983. Structure and modulation of neural cell adhesion molecules in early and late embryogenesis. Cold Spring Harbor Symposium on Quantitative Biology 68:515-525.
Chuong, C.-M., McClain, D.A., Streit, P., and Edelman, G.M. 1982. Neural cell adhesion molecules in rodent brains isolated by monoclonal antibodies with cross-species reactivity. Proc. Natl. Acad. Sci. USA 79:4324-4328.
Edelman, G.M. and Chuong, C.-M. 1982. Embryonic to adult conversion of neural cell adhesion molecules in normal and staggerer mice. Proc. Natl. Acad. Sci. USA 79:7036-7040.
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Plikus MV, Baker RE, Chen CC, Fare C, de la Cruz D, Andl T, Maini PK, Millar SE, Widelitz R, Chuong CM. Self-organizing and stochastic behaviors during the regeneration of hair stem cells. Science 332:586-589, 2011. Supporting On-line Materials Movie 1 Movie 2 Movie 3 Movie 4 Movie 5 Movie 6 Movie 7 Movie 8 Movie 9
Jiang TX, Tuan TL, Wu P, Widelitz RB, Chuong CM. From buds to follicles: Matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis. Differentiation. 2011.
Hughes MW, Wu P, Jiang TX, Lin SJ, Dong CY, Li A, Hsieh FJ, Widelitz RB, Chuong CM. In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages. Integr Biol (Camb). 3:388-407, 2011.
Lee LF, Jiang TX, Garner W, Chuong CM. A simplified procedure to reconstitute hair-producing skin Tiss Eng Part C 17:1-10, 2011.
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2010
Al-Nuaimi Y, Baier G, Watson RE, Chuong CM, Paus R. The cycling hair follicle as an ideal systems biology research model.Exp Dermatol. 19:707-713, 2010.
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2009
Yeh J, Green LM, Jiang TX, Plikus M, Huang E, Chang RN, Hughes MW, Chuong CM, Tuan TL.Accelerated closure of skin wounds in mice deficient in the homeobox gene Msx2.Wound Repair Regen. 17:639-648, 2009.
Lin CM, Jiang TX, Baker RE, Maini PK, Widelitz RB, Chuong CM. Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation. Dev. Biol. 334:369-382, 2009.
Rubenstein M, Sai Y, Chuong CM, Shen WM. Regenerative patterning in Swarm Robots: mutual benefits of research in robotics and stem cell biology. Int J Dev Biol. 53:869-881, 2009.
Richardson, MK and Chuong, C-M. Regeneration and pattern formation - an interview with Susan Bryant. Int J Dev Biol. 53:827-833, 2009.
Chang C, Wu P, Baker RE, Maini PK, Alibardi L, Chuong CM. Reptile scale paradigm: Evo-Devo, pattern formation and regeneration. Int J Dev Biol. 53:813-26, 2009.
Chuong CM, Widelitz RB. The river of stem cells. Cell Stem Cell. 4:100-102, 2009.
Lee LF, Chuong CM. Building complex tissues: high-throughput screening for molecules required in hair engineering. Invest Dermatol, 129:815-7, 2009
Plikus MV, Widelitz RB, Maxson R, Chuong CM. Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity. Int J Dev Biol. 2009.
Li, MY. The master of chicken feather and duck bill research: Cheng-Ming Chuong. Sci. Am. (Chinese version) 84:114-119, 2009.
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2008
Plikus MV, Mayer JA, de la Cruz D, Baker RE, Maini PK, Maxson R, Chuong CM. Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature, 451:340-4, 2008.
Mayer JA, Foley J, De La Cruz D, Chuong CM, Widelitz R. Conversion of the nipple to hair-bearing epithelia by lowering bone morphogenetic protein pathway activity at the dermal-epidermal interface. Am J Pathol. 173:1339-48, 2008.
Plikus MV, Chuong CM. Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents. J Invest Dermatol 128:1071-80, 2008.
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2007
Widelitz RB, Veltmaat JM, Mayer JA, Foley J, Chuong CM. Mammary glands and feathers: comparing two skin appendages which help define novel classes during vertebrate evolution. Semin Cell Dev Biol. 18:255-66, 2007.
Chuong CM. Regenerative biology: new hair from healing wounds. Nature. 447:265-266, 2007.
Wang XP, Suomalainen M, Felszeghy S, Zelarayan LC, Alonso MT, Plikus MV, Maas RL, Chuong CM, Schimmang T, Thesleff I. An integrated gene regulatory network controls stem cell proliferation in teeth. PLoS Biol.5:e159, 2007.
Drew FC, Lin CM, Jiang TX, Blunt G, Mou C, Chuong CM, Headon DJ. The Edar subfamily in feather placode formation. Developmental Biology 305:232-45, 2007.
Chuong CM, Cotsarelis G, Stenn K. Defining hair follicles in the age of stem cell bioengineering. J Invest Dermatol, 127:2098-100, 2007.
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2006
Yue Z, Jiang TX, Widelitz RB, Chuong CM. Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia. Proc Natl Acad Sci U S A. 103:951-5, 2006.
Wu P, Jiang TX, Shen JY, Widelitz RB, Chuong CM. Morphoregulation of avian beaks: comparative mapping of growth zone activities and morphological evolution. Dev. Dyn. 235:1400-12, 2006.
Chuong CM, Dhouailly D, Gilmore S, Forest L, Shelley WB, Stenn KS, Maini P, Michon F, Parimoo S, Cadau S, Demongeot J, Zheng Y, Paus R, Happle R. What is the biological basis of pattern formation of skin lesions? Exp Dermatol. 15:547-64, 2006.
Widelitz RB, Baker RE, Plikus M, Lin CM, Maini PK, Paus R, Chuong CM. Distinct mechanisms underlie pattern formation in the skin and skin appendages. Birth Defects Res C Embryo Today. 78:280-91, 2006.
Plikus MV, Zhang Z, Chuong CM. PubFocus: semantic MEDLINE/PubMed citations analytics through integration of controlled biomedical dictionaries and ranking algorithm. BMC Bioinformatics. 2;7:424, 2006.
Plikus, MV, Sundberg, JP and Chuong, CM. Mouse Skin Ectodermal Organs. In The Mouse in Biomedical Research, Academic Press. NY. Volume III Normative Biology, Husbandry, and Models. 2006.
Lin CM, Jiang TX, Widelitz RB, Chuong CM. Molecular signaling in feather morphogenesis. Curr Opin Cell Biol. 18:730-41, 2006.
Maini PK, Baker RE, Chuong CM. Developmental biology. The Turing model comes of molecular age. Science. 314:1397-8, 2006.
Chuong, C-M., Wu, P., Plikus MV, Jiang, TX, Widelitz, RB. Engineering Stem cells into organs: Topobiological transformations demonstrated by beak, feather and other ectodermal organ morphogenesis. Current Topics in Developmental Biology. 237-74, 2006.
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2005
Yue ZC, Jiang TX, Widelitz RB, Chuong CM. Mapping Stem Cell Activities in the Feather Follicle. Nature 438:1026-1029, 2005.
Plikus, MV., Zeichner-David, M., Mayer, J.A., Reyna, J., Bringas, P., Thewissen, J. G. M., Snead, ML., Chai, Y.,Chuong, CM "Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity". Evolution and Development. 7:440–457, 2005.
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2004
Hou, L., Chiappe, L.M., Zhang, F., and Chuong, C-M. New Early Cretaceous fossil from China documents a novel trophic specialization for Mesozoic birds. Naturwissenschaften. 91: 22-25, 2004.
Suksaweang, S., Lin C-M., Jiang, T-X., Hughes, M.W., Widelitz, R.B., and Chuong, C-M. Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation. Dev Biol. 266:109-122, 2004.
Plikus M, Wang WP, Liu J, Wang X, Jiang TX, Chuong CM. Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway. Am J Pathol. 164:1099-114, 2004.
Plikus M, Chuong CM. Making waves with hairs. J Invest Dermatol. Apr;122:vii-ix, 2004.
Chang, C.-H., Yu, M., Wu, P., Jiang, T.-X., Yu, H.-S., Widelitz, R.B., and Chuong, C.-M. Sculpting Skin Appendages Out of Epidermal Layers Via Temporally and Spatially Regulated Apoptotic Events. J. Invest. Dermato. 122: 1348-1355, 2004.
Shen, W.-M., P. Will, A. Galstyan, C.-M. Chuong, Hormone-inspired self-organization and distributed control of robotic swarms. Autonomous Robots, 17, 93-105, 2004.
Wu, P. Hou, L. Plikus, M, Hughes, M., Scehnet, J., Suksaweang, S., Wideltz, RW., Chuong, CM. Evo-Devo of amniote integuments and appendages. Int. J. Developmental Biol. 48:249-270, 2004.
Jiang, T-X., Wideltz, RB., Shen, WM., Will, P., Wu, DY., Lin, CM., Jung, JS., Chuong, CM. Integument pattern formation involves genetic and epigenetic controls operated at different levels: Feather arrays simulated by a digital hormone model. Int. J. Developmental Biol. 48:117-136, 2004.
Yu, M., Yue, Z., Wu, P., Wu, D.-Y., Mayer, J.A., Medina, M., Widelitz, R.B., Jiang, T.-X., and Chuong, C.-M. The developmental biology of feather follicles. Int. J. Developmental Biol. 48:181-191, 2004.
Wu, P., Jiang, T.-X., Suksaweang, S, Wideltz, RB., Chuong, CM. Molecular Shaping of the Beak. Science, 305:1465-1466, 2004. Supplement
Mayer, JA., Chuong, CM., Widelitz, R. Rooster feathering, androgenic alopecia, and hormone dependent tumor growth: What is in common? Differentiation. 72: 474-488, 2004.
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2003
Chodankar R., Chang C-H, Yue Z., Suksaweang S., Burrus L., Chuong C-M, and Widelitz RB. Shift of Localized Growth Zones Contributes to Skin Appendage Morphogenesis: Role of the Wnt/Beta-catenin Pathway. J Inv Dermatol. 120:19-26, 2003.
Chuong, C-M. Homeobox Genes, Fetal Wound Healing, and Skin Regional Specificty. J Invest Dermatol. 120:9-11, 2003.
Chuong, C-M and Homberger, D.G. Development and Evolution of the Amniote Integument: Current Landscape and Future Horizon. J Exp Zool. 298B: 1-11, 2003.
Chuong, C-M, Wu, P., Zhang, F-C, Xu, X., Yu, M., Widelitz, R.B., Jiang, T-X, and Hou, L. Adaptation to the Sky: Defining the Feather With Integument Fossils From Mesozoic China and Experimental Evidence From Molecular Laboratories. J Exp. Zool. 298B: 42-56, 2003.
Widelitz, R.B., Jiang, T-X, Yu, M., Shen, T., Shen, J-Y, Wu, P., Yu, Z., and Chuong, C-M. Molecular Biology of Feather Morphogenesis: A Testable Model for Evo-Devo Research. J Exp Zool. 298B: 109-122, 2003.
Hughes, M.W., and Chuong, C-M. A Mouthful of Epithelial-Mesenchymal Interactions. J Invest Dermatol. 121:vii-viii, 2003.
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2002
Chuong C-M. Development, Tissue Engineering, and Cancer: Guidance of Stem Cells. Changhua J Med. 7: 1-7, 2002.
Koh S., Li H., Lee Y-H, Widelitz R.B., Chuong C-M., and Stallcup M.R. Synergistic Coactivator Function by Coactivator-associated Arginine Methyltrasferase (CARM) 1 and Beta-Catenin with Two Different Classes of DNA-binding Transcriptional Activators. J. Biol. Chem. 277: 26031-26035, 2002.
Chuong C-M, Nickloff BJ, Elias PM, Goldsmith LA, Macher E., Maderson PA., Sundberg JP., Tagami H., Plongka PM., Thestrup-Pedersen K., Bernard BA., Scroder JM., Dotto P., Chang C-H., Williams ML., Feingold KR., King LE., Kligman AM., Rees JL., Christophers E. What is the ‘true’ function of skin. Exp. Dermatol. 11:159-87, 2002.
Ma L., Liu J., Wu T., Plikus M., Jiang T.-X, Liu Y-H, Muller-Rover S., Brissette J., Peters H., Maxson R., Maas R., and Chuong C-M. Cyclic alopecia in Msx2 mutants: Defects in hair cycling and hair shaft differentiation. Development and Disease. 130:379-389, 2002.
Shen, W-M, and Chuong, C-M. Simulating Self-Organization with the Digital Hormone Model. Multi-Robot Systems: From Swarms to Intelligent Automata., (A. Schultz and L. Parker, eds.), Kluwer Academic Publishers, 2002.
Shen, W-M, Chuong, C-M, and Will, P. Digital Hormone Models For Self-Organization. International Conference on Simulation and Synthesis of Living Systems. Sydney Australia, 2002.
Shen, W-M, Chuong, C-M, and Will, P. Simulating Self-Organization for Multi-Robot Systems. International Conference on Intelligent and Robotic Systems. Switzerland, 2002.
Yu M, Wu P, Widelitz RB, and Chuong C-M. The Morphogenesis of feathers. Nature. 420:308-312, 2002.
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2001
Lin, S-L, Chuong,C-M, and Ying, S-Y. A Novel mRNA-cDNA Interference Phenomenon for Silencing bcl-2 Expression in Human LNCaP Cells" Biochem. Biophysi. Res. Comm. 281:639-644, 2001.
Lin S-L and Ying S-Y. DRNAi (Messenger RNA-antisense DNA Interference) as a Novel Defense System Against Cancer and Viral Infections. Current Cancer Drugs Targets. 1:241-247, 2001.
Chuong, C-M, Hou, L.H., Chen, PJ, Wu, P., Patel, N, and Chen, YP. Dinosaur’s feather and Chicken’s tooth? Tissue engineering of the integument. John Ebbling lecture. Eur. J. Dermatology. 11:286-292, 2001.
Hsu Y.-H, Shaw C.-K, Chuong CM. Immunohistochemical localization of deleted-in-colon-cancer (DCC) protein in human epithelial, neural, and neuro-endocrine tissues in paraffin sections with antigen retrieval. Kaohsiung J Med Sci 17:351-357, 2001 (Abstract).
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2000
Chuong, C.-M. Skin Morphogenesis: Embryonic chicken skin explant cultures. In Tuan and Lo edit: Developmental Biology Protocols. Vol. 2. In Methods in Molecular Biology Series,. Humana Press Inc. Totowa, NJ. Pp. 101-106, 2000.
Stott. S. and Chuong, C.-M. Application of retroviral gene transduction to limb bud micromass cultures. In Tuan and Lo edit: Developmental Biology Protocols. Vol. 1. In Methods in Molecular Biology Series,. Humana Press Inc. Totowa, NJ. Pp 509-513, 2000.
Widelitz, R.B., Jiang, T.-X., Lu, J.-F. and Chuong, C.-M. Beta catenin in epithelial morphogenesis: Conversion of part of avian foot scales into feather buds with a mutated beta catenin. Dev. Biol. 219:98-114, 2000.
Chen, J. and Chuong, C.-M. Dynamic expression of lunatic fringe during feather morphogenesis: a switch from medial-lateral to anterior-posterior asymmetry. Mechanism of Development. 91:351-354, 2000.
Wu, T. and Chuong, C.-M. Developmental Biology of Skin Appendages. In Camacho, F., Randall, V.A., and Price, V.H. edit Hair Biology and Disorders: Research, Pathology and Management. Martin Dunitz Pub. Pp 17-37, 2000.
Chen, Y.P., Zhang, Y., Jiang, T.X., Barlow, A., Amand, TR, Hu, Y., Heaney, S., Francis- West, P., Chuong, C.M., and Maas, R. Conservation of early odontogenic signaling pathway in Aves. Proc. Natl. Acad. Sci. 97: 10044-10049, 2000.
Chuong, C-M, Chodankar, R., Widelitz, R.B., Jiang, T. X. Evo-Devo of Feathers and Scales: Building complex epithelial appendages. Current Opinion in Development and Genetics. 10:449-456, 2000.
Chuong, C-M, Lin, J., Patel, N., Jung H-S., Widelitz, R. B. Sonic Hedgehog signaling pathway in vertebrate epithelial organ formation: Perspectives in development and evolution. Cellular and Molecular Life Sciences. 57:1672-1681, 2000.
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1999
Chuong, C.-M., Jung, H.-S. and Widelitz, R.B. Lineage and pluripotentiality of epithelial precursor cells in developing chicken skin. Biochemistry and Cell Biology 76:1069-1077, 1999.
Widelitz, R.B., Jiang, T.-X, C.-W.J., Stott, N.S. and Chuong, C.-M. Wnt-7a in feather morphogenesis: Involvement of anterior-posterior asymmetry and proximal-distal elongation demonstrated with an in vitro reconstitution model. Development. 126:2577-2587, 1999.
Jiang, T.-X., Jung, H.S., Widelitz, R.B., Chuong, C.-M. Self organization of periodic patterns by dissociated feather mesechymal cells and the regulation of size, number and spacing of primordia. Development. 126:4997-5009, 1999.
Stott, S., Jiang, T-X., and Chuong, C.-M. Successive formative stages of Precartilage mesenchymal condensations in vitro: Modulation of cell adhesion by wnt-7a and BMP-2. J. Cell Physiology. 180:314-324, 1999.
Wang, W.P.,Kasahara, N., Chuong, C.M. Update to Retroviral Gene transfer in chondrogenic limb bud micromass cultures: Adenoviral mediated gene transfer. In McClelland, M and Pardee, A. B. edit. 1999. Expression Genetics: Accelerated and High-Throughput Methods. Biotechnique Books. Eaton Publishing. Pp363-364, 1999.
Ying, S.Y., Lui, H.M., Lin. S.L., and Chuong, C.M. Generation of full length cDNA library from single human prostate cancer cells. Biotechniques. 27:410 - 414, 1999.
Lin, S.-L., Chuong, C.-M., Widelitz, R.B., Ying, S.Y. In vivo analysis of cancerous gene Expression by RNA polymerase chain reaction. Nucleic Acids Res. 27:4585-4589, 1999.
Ying, S.-Y., Chuong, C.-M., and Lin, S.-L. Suppression of activin-induced apoptosis by novel antisense strategy in human prostate cancer cells. Biochem Biphy. Res. Comm. 265:669-673, 1999.
Jiang, T.-X., Liu, Y.H., Widelitz, R.B., Kundu, R.K., Maxson, R.E. and Chuong, C.-M. Epidermal dysplasia and abnormal hair follicles in transgenic mice over-expressing homeobox gene Msx-2. J. Investigative Demato. 113:231-238, 1999.
Chuong, C.-M. and Noveen, A. Phenotypic determination of epithelial appendages: Genes, developmental pathways and evolution. J Invest Dermatol. 4:307-311, 1999.
Chen, C.-W. J. and Chuong, C.-M. Avian integument provides multiple possibilities to analyze different phases of skin appendage morphogenesis. J Invest Dermatol. 4:333-337, 1999.
Widelitz, R.B. and Chuong, C.-M. Early events in skin appendage formation: induction of epithelial placodes and condensation of dermal mesenchymal cells. J Invest Dermatol. 4:302-306, 1999.
Wang, W.-P., Widelitz, R.B., Jiang, T.-X. and Chuong, C.-M. Msx-2 and the regulation of organ size: epidermal thickness and hair length. J Invest Dermatol. 4:278-281, 1999.
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1998
Stott, S., Lee, Y.S. and Chuong, C.M. 1998. Retroviral gene transfer in micromass cultures: Potential for genetic manipulations in organotypic cultures. Biotechniques. 24:660-666.
Lee, Y.S., Stott, S., Jiang, T.-X., Widelitz, R.W. and Chuong, C.-M. 1998. Early events during precartilage condensation formation in limb bud micromass cultures: Application of retrovirus-mediated gene perturbation. Cells and Materials.8:19-32
Jung, H-S., Francis-West, F., Widelitz, R.B.,T.-X., Ting-Berreth, S., Tickle, C., Wolpert, L., and Chuong, C.-M. 1998. Local inhibitory action of BMPs and their relationships with activators in feather formation: Implications for periodic patterning. Dev. Biol. 196:11-23.
Chuong, C.-M. 1998. Feather Morphogenesis: A Model of the Formation of Epithelial Appendages. In Chuong edit, Molecular Basis of Epithelial Appendage Morphogenesis. Landes Bioscience. Austin. pp3-14.
Noveen, A., Hartenstein, V. and Chuong, C.-M. 1998. Gene networks and supernetworks: Evolutionary conserved gene interactions. In Chuong edit, Molecular Basis of Epithelial Appendage Morphogenesis. Landes Bioscience. Austin. pp371-391.
Jiang, T.-X., Stott, S., Widelitz, R. B. and Chuong, C.-M. 1998. Current methods in the study of avian skin appendages. In Chuong edit, Molecular Basis of Epithelial Appendage Morphogenesis. Landes Bioscience. Austin. pp395-408.
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1997
Lee, Y. S. and Chuong C-M. 1997. Activation of protein kinase A is a pivotal step involved in both BMP-2- and cAMP-induced chondrogenesis. J. Cell Physiol. 170:153-165.
Chen, C. J., Jung, H.-S, Jiang, T.-X. and Chuong, C.-M. 1997. Asymmetric expression of Notch, Serrate and Delta is associated with the anterior - posterior axis of feather buds. Developmental Biology. 188:181-187.
Widelitz, R. B., Jiang, T.-X., Noveen, A., Ting-Berreth, S. A., Yin, E., Jung, H-S, and Chuong, C.-M. 1997. Molecular histology in skin appendage Morphogenesis. J. Microscopy Research and Techniques. 38:452-465.
Lu, J. F., and Chuong, C.-M. Widelitz, R.W. 1997. Characterization of chicken catenin shows unique expression patterns in sites of epithelial-mesenchymal interaction. Gene. 196:201-207.
Combates, N. J., Chuong, C.-M., Stenn, K. S., and Prouty, S. M. 1997. Expression of Two Ig Family Adhesion molecules in the murine hair cycle: Enrichment of DCC in the bulge epithelia and constancy of NCAM in the follicular papilla. J. Invest. Dermatol. 109:672-678.
Stott, S. and Chuong, C.-M. 1997. Dual action of sonic hedgehog on chondrocyte hypertrophy: retrovirus mediated ectopic sonic hedgehog expression in limb bud micromass culture induces novel cartilage nodules that are positive for alkaline phosphatase and type x collagen. J. Cell Science.110:2691-2701.
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1996
Noveen, A., Jiang, T.-X., and Chuong, C.-M. 1996. cAMP, an activator of protein kinase A (PKA), suppresses the expression of sonic hedgehog. BBRC. 219:180-185.
Chuong, C.-M., Widelitz, R. W., Ting-Berreth, S. A. and Jiang, T.-X. 1996. Early Events During the Regeneration of Skin Appendages: Dependence of Epithelial-mesenchymal Interaction and Order of Molecular Reappearance. J. Investigative. Dermato. 107:639-646.
Ting-Berreth, S. A. and Chuong, C.-M.. 1996. Sonic hedgehog in feather morphogenesis: Induction of mesenchymal condensation and association with cell death. Dev. Dynamics.207:157-170.
Ting-Berreth, S. A. and C. M. Chuong. 1996. Local delivery of TGF beta2 can restore epithelium dependent organization of mesenchymal condensation during skin appendage morphogenesis. Dev. Biol. 179:347-359
Widelitz, R. B., Jiang, T.-X., Noveen, A., Chen, C.-W. J. and Chuong, C.-M. 1996. FGF induces new feather buds from developing avian skin. J. Investigative. Dermato. 107:797-803.
Chuong, C.-M. 1996. Signaling network in skin appendage induction. Second International Conference on Alopecia. International Business Communications. Southborough, MA.
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1995
Noveen, A., Jiang, T.-X. Ting-Burreth, S. A., and Chuong, C.-M. 1995. Homeobox genes Msx-1 and Msx-2 are associated with induction and growth of skin appendages. J. Invest. Dermato. 104:711-719.
Noveen, A. Jiang, T.-X. and Chuong, C.-M. 1995. Protein kinase A and protein kinase C modulators have reciprocal effects on mesenchymal condensation during skin appendage morphogenesis. Dev. Biol. 171:677-693.
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1994
Shankar, K. R., Chuong, C.-M., Jaskoll, T. and Melnick, M. 1994. Effect of in ovo retinoic acid exposure on cephalic neural crest cell migration: In vitro emigration analysis and reciprocal alteration of HNK-1 and N-CAM. Develpmental Dynamics. 200:89-102.
Chuong, C.M., Jiang, T.-X., Yin, E., Widelitz, R.B. 1994. cDCC is an epithelial cell adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction. Developmental Biology. 164:383-397.
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1993
Pacifici, M., Iwnamoto, Golden, E., Leatherman, J. L., Lee, Y.-S., Chuong, C.-M. 1994. Tenascin is involved in articular cartilage development. Developmental Dynamics, 198:123-134.
Chuong, C. M., Widelitz, R. B., Jiang, T. X., 1993. Adhesion molecules and homeoproteins in the phenotypic determination of skin appendages. J. Investigative. Dermatol. 101:10S-15S.
Widelitz, R., Jiang, T. X., Murray, B. and Chuong, C. M. 1993. Neural cell adhesion molecules (NCAM) mediate precartilaginous condensations and enhances chondrogenesis during chicken limb development. J. Cell Physiol. 156: 399-411.
Chuong, C.-M., Widelitz, R. B., Jiang, T. X., Abbott, U., Lee, Y. S. and Chen, H. M. 1993. Roles of adhesion molecules NCAM and tenascin in limb chondrogenesis. Proceedings of the 4th International Conference of Limb Development and Regeneration. pp 2165-2174. (Abstract)
Jiang, T. X., Yi, J. R., Ying, S. Y. and Chuong, C. M. 1993. Activin enhances chondrogenesis of limb bud cells: stimulation of precartilagenous mesenchymal condensations and expression of NCAM. Dev. Biol. 155:545-557.
Chuong, C.-M. 1993. The making of a feather: Homeoproteins, retinoids and adhesion molecules. BioEssays. 15:513-521.
Serras, F., Fraser, S. and Chuong, C.-M. 1993. Asymmetric patterns of gap junctional communication in developing skin demonstrated by micro-injection of Lucifer Yellow. Development. 119:85-96.
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1992
Jiang, T.-X. and Chuong, C.-M. 1992. Mechanism of feather morphogenesis: I. Analyses with antibodies to Adhesion Molecules Tenascin, N-CAM and Integrin. Dev. Biol. 150:82-98.
Chuong, C.-M., Ting, S. A., Widelitz, R. B. and Lee, Y.S. 1992. Mechanism of Skin Morphogenesis: II. Retinoic acid gradient modulates axis orientation and phenotypes of skin appendages. Development. 115:839-852.
Widelitz, R. B., and Chuong, C.-M. 1992. Replication-defective virus infection of feather buds produces a localized region of beta-galactosidase activity. Biochem. Biophysi. Res. Comm. 186:1020-1024.
Lee, Y.-L. and Chuong, C,-M. 1992. Adhesion Molecules in skeletogenesis. I. Transient expression of N-CAM in osteoblasts during endochondral and intramembranous ossification. J. Bone and Mineral Res. 7:1435-1446.
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1991
Chuong, C.-M. and Chen, H.-M. 1991. Enhanced expression of N-CAM and tenascin during wound healing. Am. J. Pathol. 138:427-440.
Chuong, C.-M., Chen, H.M., Jiang, T.X., Chia, J. 1991. Adhesion molecules in skin development: Morphogenesis of feather and hair. Ann. New York Acad. Sci. 642:263-280.
Chuong, C.-M., J. 1991. Position specific expression of homeoprotein gradients in different feather tracts. Ann. New York Acad. Sci. 642:462-464.
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1990
Chuong, C.-M. 1990a. Adhesion molecules N-CAM and tenascin in embryonic development and tissue regeneration. J. Craniofacial Genetics and Developmental Biology. 10:147 -161. (Abstract)
Chuong, C.-M. 1990b. Differential roles of multiple adhesion molecules in cell migration: Granule cell migration in cerebellum. Experientia. 46:892 - 899.
Chuong, C.-M., Oliver, G., Ting, S. Jegalian, B., Chen, H.M. and De Robertis, E.M. 1990. Gradient of homeoproteins in developing feather buds. Development 110:1021-1030.
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1982-1988
Fraser, S.E., Carhart, M.S., Murray, B.A., Chuong, C.-M., and Edelman, G.M. 1988. Alterations in the Xenopus Retinotectal Projection by Antibodies to Xenopus N-CAM. Developmental Biology 129:217-230.
Richardson, G., Crossin, K.L., Chuong, C.-M., and Edelman, G.M. 1987. Expression of cell adhesion molecules in embryonic induction: III. Development of the otic placode. Dev. Biol. 119:217-230.
Chuong, C.-M., Crossin, K.L., and Edelman, G.M. 1987. Sequential expression and differential functions of multiple adhesion molecules during the formation of cerebellar cortical layers. J. Cell Biol. 104:331-342.
Crossin, K.L., Richardson, G.P., Chuong, C.-M., and Edelman, G.M. 1987. Modulation of adhesion molecules during induction and differentiation of the auditory placode. Functions of the Auditory System., (G.M. Edelman, W.E. Gall, and W.M. Cowan, eds.), Wiley.
Daniloff, J., Chuong, C.-M., Levi, G., and Edelman, G.M. 1986. Differential distribution of cell adhesion molecules during histogenesis of the chicken nervous system. J. Neuro. Sci. 6:739-758.
Hoffman, S., Friedlander, D.R., Chuong, C.-M., Grumet, M., and Edelman, G.M. 1986. Differential contributions of Ng-CAM and N-CAM to cell adhesion in different neural regions. J. Cell Biol. 103:145-158.
Gallin, W.J., Chuong, C.-M., Finkel, L.H., and Edelman, G.M. 1986. Antibodies to L-CAM perturb inductive interactions and alter feather pattern and structure. Proc. Natl. Acad. Sci. USA 83:8235-8239.
Chuong, C.-M., and Edelman, G.M. 1985a. Expression of cell adhesion molecules in embryonic induction. I. Morphogenesis of nestling feathers. J. Cell Biol. 101:1009-1026.
Chuong, C.-M., and Edelman, G.M. 1985b. Expression of cell adhesion molecules in embryonic induction. II. Morphogenesis of nestling feathers. J. Cell Biol. 101:1027-1043.
Crossin, K.L., Chuong, C.-M., and Edelman, G.M. 1985. Expression sequences of cell adhesion molecules. Proc. Natl. Acad. Sci. USA 82:6942-6946.
Chuong, C.-M., and Edelman, G.M. 1984. Alteration in neural cell adhesion molecules during development of different regions of the nervous system. J. Neuro. Sci. 4:2354-2368.
S E Fraser, B A Murray, C M Chuong, and G M Edelman. 1984. Alteration of the retinotectal map in Xenopus by antibodies to neural cell adhesion molecules. Proc Natl Acad Sci U S A. 81:4222–4226.
Hoffman, S., Chuong, C.-M., and Edelman, G.M. 1984. Evolutionary conversation of key structures and binding functions of neural cell adhesion molecules. Proc. Natl. Acad. Sci. USA 81:6881-6885.
Grumet, M., Hoffman, S., Chuong, C.-M., and Edelman, G.M. 1984. Polypeptide components and binding functions of neuron-glia cell adhesion molecules. Proc. Natl. Acad. Sci. USA 81:7989-7993.
Chuong, C.-M. 1983. Neural cell adhesion molecules in the development of the brain. Ph.D. Thesis, The Rockefeller University, New York.
Edelman, G.M., Hoffman, S., Chuong, C.-M., Thiery, J.-P., Brackenbury, R., Gallin, W.J., Grumet, M., Greenberg, M., Hemperly, J., Cohen, C., and Cunningham, B.A. 1983. Structure and modulation of neural cell adhesion molecules in early and late embryogenesis. Cold Spring Harbor Symposium on Quantitative Biology 68:515-525.
Chuong, C.-M., McClain, D.A., Streit, P., and Edelman, G.M. 1982. Neural cell adhesion molecules in rodent brains isolated by monoclonal antibodies with cross-species reactivity. Proc. Natl. Acad. Sci. USA 79:4324-4328.
Edelman, G.M. and Chuong, C.-M. 1982. Embryonic to adult conversion of neural cell adhesion molecules in normal and staggerer mice. Proc. Natl. Acad. Sci. USA 79:7036-7040.
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@Cheng-Ming
Chuong
May 2011
May 2011