Publications:


Park-Lee, S., Kim, S., Laird-Offringa, I.A. (2003) Characterization of the interaction between neuronal RNA-binding protein HuD and AU-rich RNA (Submitted for publication)


Tsou, J.A., Shen, L.Y.C., Siegmund, K.S., Long, T.I., Laird, P.W., Seneviratne, C., Koss, M.N., Pass, H.I., Hagen, J.A., Laird-Offringa, I.A. (2003) Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung. (Submitted for publication)


Li, H., Park, S., Kilburn, B., Jelinek, M.A., Henschen-Edman, A., Aswad, D.W., Stallcup, M.R., Laird-Offringa, I.A. (2002) Lipopolysaccharide-induced modification of HuR. J. Biol. Chem. 277, 44623-44630.


Tsou, J.A., Hagen, J.A., Carpenter, C.L., Laird-Offringa, I.A. (2002) DNA methylation analysis: a powerful new tool for lung cancer diagnosis. Oncogene 21, 5450-5461.


Katsamba, P.S., Bayramyan, M., Haworth, I.S., Myszka, D.G., Laird-Offringa, I.A. (2002) Complex role of the beta2-beta3 loop in the interaction of U1A with U1 hairpin II RNA. J. Biol. Chem. 277, 33267-33274.


Virmani, A.K, Tsou, J.A., Siegmund, K.D., Shen, L.Y.C., Long, T.I., Laird, P.W., Gazdar, A.F., Laird-Offringa, I.A. (2002) Hierarchical clustering of lung cancer cell lines using DNA methylation markers. Cancer Epid. Biom. Prev. 11, 291-297.


Katsamba, P.S., Park, S., Laird-Offringa, I.A. (2002) Kinetic studies of RNA-protein interactions using surface plasmon resonance. Methods, 26, 95-104.


Katsamba, P.S., Myszka, D.G., Laird-Offringa, I.A. (2001)Two functionally distinct steps mediate high affinity binding of U1A protein to U1 hairpinII RNA. J.Biol.Chem., Vol.276,24, 21476-21481.


Bernasconi, N.L., Wormhoudt, T.A.M., and Laird-Offringa, I.A. (2000). Post-transcriptional deregulation of myc genes in lung cancer cell lines. Am. J. Respir. Cell Mol. Biol. 23, 560-565.


Park, S., Myszka, D.G., Yu, M., Littler, S.J., Laird-Offringa, I.A. (2000) HuD RNA-binding Domains Play Distinct Roles in the Formation of a Stable Complex with AU-rich RNA. Molecular and Cellular Biology 20:4765-4772.


Laird-Offringa, I.A. (1999)In vitro genetic analysis of RNA-binding proteins using phage display In: "RNA-protein interaction protocols", a volume of Methods in Molecular Biology, edited by Susan Haynes. (Humana Press, NJ) p189-216.


Laird-Offringa, I.A. and Belasco, J.G. (1998).RNA-binding proteins tamed Nature Structural Biology 5, 665-668.


Laird-Offringa, I. A. (1997) Analysis of RNA-binding proteins using phage display. In "Analysis of mRNA Formation and Function", a volume of Methods in Molecular Genetics, edited by Joel Richter. (Academic Press, FL). p 211-236.