Last updated 3/8/00

YEAR 1 MEDICAL STUDENT NEUROANATOMY/NEUROPHYSIOLOGY

     This is an intensive 7 week course (please see schedule below) in Human Neuroanatomy  and Neurophysiology taught within the first year Medical Student Neurosciences class. The course consists of lectures in neuroanatomy and basic neurophysiology, plus two hour laboratory sessions that complement the majority of the lectures.   Clinical Correlation lectures are also offered by clinician specialists in particular subject areas.

     The object of this course is to provide students with a conceptualization of how the normal central nervous system functions and integrates with the other systems of the body. Neuroanatomy primarily involves training in basic anatomical skills. The first of these is the development and acquisition of a spatial concept of the important, and ultimately clinically relevant, elements of the nervous system. This includes investigation of the location of important elements of the nervous system, their relationships to one another and their connectivity, and emphasizes their individual functional roles in nervous system operation. The second is the skill necessary to recognize nervous system malfunction, and to provide the vocabulary necessary to allow professional communication (including both written and oral presentations of research topics) related to nervous system disease. In order to acquire these skills, lectures, videotapes, and films are used. Textual material is presented in the form of a detailed syllabus, atlases, and exercise books. Reinforcement is provided through laboratory work with whole human brains, stained microscope slides of key sections through human brain and spinal cord, models, 35 mm slides, videodiscs and computer programs, radiographs, including CAT scans, MRI images, and photographs of histochemical localization within the brain. Neuroanatomy actively involves the integration of structural with physiological and biochemical concepts, as well as correlations with selected clinical cases. In addition, within the neuroanatomy classes themselves, functional, neurochemical, or clinical correlations are frequently made. An effort is made to integrate didactic material with case-study presentations that are problem-oriented. Finally, consideration and integration is made with other organ systems of the body that bear directly on the normal function of the nervous system, as well as a consideration of those systems which come under nervous or neuroendocrine control.

Course Director:

       Judy A. Garner, Ph.D. , Associate Professor, Cell and Neurobiology, 442-1279, jgarner@hsc.usc.edu  

Contributing Faculty, Neuroanatomy lectures and laboratories:

       Roscoe Atkinson, M.D., Assistant Professor, Pathology, 442-2736, ratkinso@hsc.usc.edu

       Robert Cabelli, Ph.D., Assistant Professor, Cell and Neurobiology, 442-6640, cabelli@hsc.usc.edu       

      Wendy Gilmore, Ph.D., Associate Professor, Neurology; Cell and Neurobiology, 442-1054, wgilmore@zygote.hsc.usc.edu

       Judy A. Garner, Ph.D., Associate Professor, Cell and Neurobiology, 442-1279, jgarner@hsc.usc.edu  

       Charles Haun, Ph.D., Associate Professor, Cell and Neurobiology,  442-1854, chaun@hsc.usc.edu

Contributing Faculty, Physiology lectures:

      Robert Chow, M.D., Ph.D., Assistant Professor, Physiology and Biophysics, rchow@hsc.usc.edu

      Robert Farley, Ph.D.,Professor, Physiology and Biophysics, 442-1240, rfarley@hsc.usc.edu

      Hans-Jürgen Fülle, M.D., Assistant Professor, Cell and Neurobiology, 442-6630, fulle@hsc.usc.edu

      Judy Garner, Ph.D., Associate Professor, Cell and Neurobiology, 442-1279, jgarner@hsc.usc.edu     

      Federico Kalinec, Ph.D.Chief, Section on Cell Structure and Function, Department of Cell and Molecular Biology, House Ear Institute

                   fkalinec@hei.org

      Dennis O'Leary, M.D., Professor, Otolaryngology, 442-2618, doleary@hsc.usc.edu

Teaching Assistants:   

      Albert Chong, Year IV Medical Student, achong@hsc.usc.edu

      Shampa De, Craniofacial Biology Graduate Student sde@hsc.usc.edu

      Brian Roehmholdt, MD/PhD Student (Year IV), roehmhol@hsc.usc.edu

      Peter Thompson, Cell and Neurobiology, Year II M.S. Student pthompso@hsc.usc.eduText:     

Texts: RECOMMENDED not REQUIRED!!!

            Young, P.A.  and Young P.H., Basic Clinical Neuroanatomy,Williams and Wilkins, 1997

            Nolte, J. The Human Brain (3rd edition) Mosby Year Book, 1993  (Not available to buy but can be purchased from upperclassmen.)

            Nolte, J. The Human Brain (4th edition) Mosby Year Book, 1999 (Available to buy at the Bookstore)

ATLASES: One is required: Either of these is very HIGHLY RECOMMENDED!!!

            Haines, D.E. Neuroanatomy: an atlas of structures, sections and systems., (4th edition) Williams and Wilkins 1995

            Watson, C. Basic Human Neuroanatomy, an introductory atlas (5th edition). Little Brown and Co., 1995

NEUROANATOMY REVIEW: For review and reference at the end of the course or for later:

            Nolte, J. The Human Brain Study Guide (4th edition)  Mosby Year Book (1999)

2000 Schedule: Please note: Schedule is NOT a standard semester schedule.

For graphical display (modified from the original by Year II Med Student Betty Shen!) of the entire Year I Neuroscience Schedule click the following:

Week 1 Schedule

Week 2 Schedule

Week 3 Schedule

Week 4 Schedule

Week 5 Schedule

Week 6 Schedule

Week 7 Schedule: Examination Week

2000 SCHEDULE
4/3 8:30-9:00 Garner Introduction to the Neurosciences System
4/3 9-10:00 Garner Introduction to Neuroanatomy I:  Gross Anatomy of the Human Brain
4/3 10-12:00 Staff NA Lab1
4/3 1-2:00 Haun Introduction to Neuroanatomy II:  Interior of Cerebrum
4/3 2-4:00 Staff NA Lab 2
4/5 8:30-9:00 Garner Sensory Receptors and Basic Sensory Physiology
4/5 9-10:00 Haun Somatic Sensation I: Touch, Vibration, and Proprioception
4/5 10-12:00 Staff NA Lab 3
4/6 10-11:00 Gilmore Reticular Formation
4/6 11-12:00 Staff NA Lab 4
4/7 10-11:00 Garner Overview of Cerebral Circulation
4/7 11-12:00 Chow Physiology of CNS Vasculature and CSF
4/10 8:30-10:00 Haun Somatic Sensation II: Pain and Temperature, Pain Suppression
4/10 10-12:00 Staff NA Lab 5
4/10 1-2:00 Farley Nerve and Synapse Review
4/10 2:00-3:00 Chow Reticular Formation, EEG and Sleep
4/12 9-10:00 Garner Sensory Cranial Nerves and Central Pathways, Visceral Afferents
4/12 10-12:00 Staff NA Lab 6
4/13 10-11:00 Garner Motor  Neurons and Spinal Reflexes
4/14 9-10:00 Garner Motor Systems I: LMNs and UMNs
4/14 10-12:00 Staff NA Lab 7
4/17 9-10:00 Garner Motor Cranial Nerves
4/17 10-12:00 Staff NA Lab 8
4/17 1-1:30 Garner Corticobulbar Pathways
4/19 9-10:00 Garner Motor Systems II: Basal Ganglia
4/19 10-12:00 Staff NA Lab 9
4/20 9-10:00 Garner Cerebellum
4/20 10-12:00 Staff NA Lab 10
4/20 2-3:00 Staff NA Problem Session I:  Case Presentations
4/24 9-10:00 Garner Cerebellar Afferent and Efferent Pathways
4/24 10-12:00 Staff NA Lab 11
4/24 1-2:00 Atkinson The Vestibular System
4/24 2-4:00 Staff NA Lab 12
4/24 4-5:00 Garner Motor Systems Summary and Review (OPTIONAL)
4/26 9-10:00 Haun CNS Vasculature
4/26 10-12:00 Staff NA LAB 13
4/27 11-12:00 O'Leary Vestibular Physiology
4/27 2-4:00 Staff PRACTICE EXAMINATION (OPTIONAL)  1hr/ student
4/28 9-10:00 Cabelli The Ear and Auditory Pathways
4/28 10-12:00 Staff NA Lab 14
5/1 9-10:00 Cabelli The Eye
5/1 1-2:00 Garner Central Visual Pathways
5/1 2-4:00 Staff NA Lab 15
5/3 9-10:00 Atkinson Thalamus
5/3 10-12:00 Staff NA Lab 16
5/4 10-11:00 Gilmore Autonomic Nervous System Physiology
5/4 11-12:00 Kalinec Auditory Physiology
5/5 9-10:00 Gilmore Hypothalamus
5/5 10-12:00 Staff NA Lab 17
5/5 1-2:30 Fülle Visual System Physiology
5/8 9-10:00 Gilmore Limbic System and Olfaction
5/8 10-12:00 Staff NA Lab 18
5/9 1-2:00 Staff NA Problem Session II: Case Presentations
5/9 3-4:00   Garner Neurophysiology Review (OPTIONAL)
5/10 9-10:00 Garner Cerebral Cortex
5/10 10-12:00 Staff NA Lab 19
5/11 10-11:00 Haun Vascular Lesions
5/11 11-12:00 Garner Cranial Nerve Review (OPTIONAL)
5/17 9-11:00 Garner NEUROANATOMY REVIEW (OPTIONAL)
5/12 1-2:30 EXAMINATION:  NEUROPHYSIOLOGY
5/19 9-12:00 EXAMINATION:  NEUROANATOMY WRITTEN
5/19 1-4:00 EXAMINATION: NEUROANATOMY PRACTICAL

Optional Clinical Correlation Lectures
4/20 1-2:00 House Otologic Anatomy
4/20 3-5:00 Wincor/Gross Sleep Dreaming and Wakefulness
4/21 11-12:00 Petzinger Motor System Disorders
4/27 1-2:00 Gross Neurotransmitters and Behavior
5/1 10-11:00 Zee Radiologic Imaging of the CNS and Skull
5/9 9-10:00 Henderson Higher Cortical Function
5/9 10-11:00 Teng Memory
5/9 11-12:00 Chui Alzheimer's Disease and Other Dementias
5/11 9-10 Amar/Heck Epilepsy and Vagus Nerve Stimulation