ZNI USC

   CHOW LABORATORY          

    Molecular Control of Regulated Secretion

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Amperometric recordings of single-vesicle exocytosis, showing “foot” signal. At right is a simulation of an amperometric event.  From Chow et al, Nature 1992

Single insulin granule exocytosis

Vesicles jumping the queue

Combined amperometric and patch clamp recording at single chromaffin cell (image from Single-Channel Recording, Sakmann and Neher, Editors) 

University of Southern California


Zilkha Neurogenetic Institute


Biophysical Society


Exocytosis and Endocytosis Subgroup of the Biophysical Society


Movie of retinal ganglion cells expressing genetically encoded calcium reporter GCaMP5 in wholemount rat retina. Stimulation using transparent (ITO) electrode array

TIRF movie of exocytosis at single cell