A. L. Wren, Ph.D.
Associate Professor of Research
Director of Research, Motion
Departments of Orthopaedic
University of Southern Calilfornia
Phone: 323-361-4120 | Fax:
323-361-1310 | Email: firstname.lastname@example.org
- B.A. Amherst College -
Computer Science (1992)
- M.S. Stanford University -
Mechanical Engineering (1994)
- Ph.D. Stanford University -
Mechanical Engineering (1997)
- Gait and motion analysis
- Development and functional
adaptation of the musculoskeletal system
- Bone density and fractures in
- Biomechanics and modeling of
muscles, tendons, and bones
Dr. Wren is a biomechanical
engineer working in clinical environment.
As Director of Research for the Motion Analysis
Laboratory at Children's Hospital Los Angeles
(CHLA), Dr. Wren conducts clinical and basic
research in several different areas of
orthopaedics. Two of the primary areas are
(1) evaluation and treatment of gait
abnormalities in children with neurologic
deficits and (2) assessment of bone density and
fractures in children. This research is
carried out in collaboration with colleagues in
Othopaedic Center as well as faculty in
the Children's Imaging Research Program.
Medical and engineering students with an
interest in orthopaedics and/or biomechanics are
encouraged to inquire about our research
programs. Contact Dr. Wren directly for
Wren TAL, Shepherd J, Kalkwarf H,
Zemel B, Lappe J, Oberfield S, Dorey FJ, Winer
K, Gilsanz V. Racial
disparity in fracture risk between white and
non-white children in the United States.
Journal of Pediatrics, epub ahead of print Sept
Wren TAL, Otsuka NY, Bowen RE,
Scaduto AA, Chan LS, Sheng M, Hara R, Kay
of gait analysis on decision-making for lower
extremity orthopaedic surgery: baseline
data from a randomized controlled trial.
Posture 34, 364-369, 2011.
Wren TAL, Gorton GE III, Ounpuu S, Tucker CA. Efficacy
of clinical gait analysis: A
systematic review. Gait and Posture
34, 149-153, 2011.
Wren TAL, Lee DC, Kay RM, Dorey FJ, Gilsanz V. Bone
density and size in ambulatory children with
cerebral palsy. Dev.
Med. Child Neurol. 53, 137-141, 2011.
Wren TAL, Lee DC, Hara R, Rethlefsen
SA, Kay RM, Dorey FJ, Gilsanz V. Effect
of high frequency, low magnitude vibration on
bone and muscle in children with cerebral
Pediatr. Orthop. 30,
Wren TAL, Cheatwood AP,
Rethlefsen SA, Hara R, Perez FJ, Kay RM. Achilles
tendon length and medial gastrocnemius
architecture in children with cerebral palsy
and equinus gait. J Pediatr.
Orthop. 30, 479-484, 2010.
Wren TAL, Kalisvaart, MM, Ghatan
CE, Rethlefsen SA, Hara R, Sheng M, Chan LS, Kay
of pre-operative gait analysis on costs and
amount of surgery. J
Pediatr. Orthop. 29, 558-563, 2009.
Wren TAL, Do KP, Hara R,
Rethlefsen SA. Use
of a patella marker to improve tracking of
dynamic hip rotation range of motion. Gait and Posture
27, 530-534, 2008.
Wren, T.A.L., Rethlefsen, S.A., and Kay, R.M.
of specific gait abnormalities in children
with cerebral palsy: Influence
of cerebral palsy subtype, age, and previous
Ped. Orthop. 25, 79-83, 2005.
Wren TAL, Liu X, Pitukcheewanont P, Gilsanz V.
densitometry in pediatric populations: discrepancies in the
diagnosis of osteoporosis by DXA and CT. J. Pediatrics
146, 776-779, 2005.
Wren TAL, Liu X, Pitukcheewanont P, Gilsanz V. Bone
acquisition in healthy children and
of dual-energy x-ray absorptiometry and
computed tomography measures. J. Clin. Endocrin.
Metabol. 90, 1925-1928, 2005.
Wren TAL, Lindsey DP, Beaupré GS, Carter
DR (2003) Effects
of creep and cyclic loading on the mechanical
properties and failure of human Achilles
tendons. Annals of Biomedical
Engineering 31, 710-717.
Wren TAL, Yerby SA, Beaupré GS, Carter DR
properties of the human Achilles tendon.
Clinical Biomechanics 16, 245-251.
October 1, 2012