Tishya Wren Publications
Children's
                    Hospital Los Angeles
Gait
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  Children's Orthopaedic Center
  John C. Wilson, Jr. Motion Analysis Laboratory
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Tishya A. L. Wren, Ph.D.

Publications


Gait Analysis & Cerebral Palsy

Wren TAL, Otsuka NY, Bowen RE, Scaduto AA, Chan LS, Sheng M, Hara R, Kay RM.  Influence of gait analysis on decision-making for lower extremity orthopaedic surgery:  baseline data from a randomized controlled trialGait and Posture 34, 364-369, 2011.

Aisen ML, Kerkovich D, Mast J, Mulroy S, Wren TA, Kay RM, Rethlefsen SA.  Cerebral palsy:  clinical care and neurological rehabilitationLancet Neurol. 10, 844-852, 2011.

Wren TAL, Gorton GE III, Ounpuu S, Tucker CA.  Efficacy of clinical gait analysis:  A systematic review.  Gait and Posture 34, 149-153, 2011.

Wren TAL, Lee DC, Kay RM, Dorey FJ, Gilsanz V.  Bone density and size in ambulatory children with cerebral palsy.  Dev. Med. Child Neurol. 53, 137-141, 2011.

Wren TAL, Lee DC, Hara R, Rethlefsen SA, Kay RM, Dorey FJ, Gilsanz V.  Effect of high frequency, low magnitude vibration on bone and muscle in children with cerebral palsy.  J Pediatr. Orthop. 30, 732-738, 2010.

Rethlefsen SA, Lening C, Wren TAL, Kay RM.  Excessive hip flexion during gait in patients with static encephalopathy:  an examination of contributing factors.  J Pediatr. Orthop. 30, 562-567, 2010.

Wren TAL, Cheatwood AP, Rethlefsen SA, Hara R, Perez FJ, Kay RM.  Achilles tendon length and medial gastrocnemius architecture in children with cerebral palsy and equinus gait.  J Pediatr. Orthop. 30, 479-484, 2010.

Huh K, Rethlefsen SA, Wren TAL, Kay RM.  Development of calcaneal gait without prior triceps surae lengthening:  an examination of predictive factors.  J Pediatr. Orthop. 30, 240-243, 2010.

Bernthal NM, Gamradt SC, Kay RM, Wren TAL, Cuomo AV, Reid J, Bales J, Otsuka NY.  Static and dynamic gait parameters before and after multilevel soft tissue surgery in ambulating children with cerebral palsy.  J Pediatr. Orthop. 30, 174-179, 2010.

Wren TAL, Tucker CA, Kay RM.  Gait analysis:  the link to clinical outcomes.  Lower Extremity Review 1, 37-41, 2009.

Wren TAL, Kalisvaart, MM, Ghatan CE, Rethlefsen SA, Hara R, Sheng M, Chan LS, Kay RM.  Effect of pre-operative gait analysis on costs and amount of surgery.  J Pediatr. Orthop. 29, 558-563, 2009.

Engsberg JR, Tucker C, Ounpuu S, Wren TA, Sisto SA, Kaufman KR.  Gait and clinical movement analysis research priorities:  2007 update from the research committee of the gait and clinical movement analysis society.  Gait and Posture 29, 169-171, 2009.

Wren TAL, Engsberg JR.  Normalizing lower extremity strength data for children with cerebral palsy.  J. Appl. Biomech. 25, 195-202, 2009.

Rethlefsen SA, Kam G, Wren TAL, Kay RM.  Predictors of outcome of distal rectus femoris transfer surgery in ambulatory children with cerebral palsy.  J. Pediatr. Orthop. B, 18, 58-62, 2009.

Wren TAL, Sheng M, Bowen RE, Scaduto AA, Kay RM, Otsuka NY, Hara R, Chan LS.  Concurrent and discriminant validity of spanish language instruments for measuring functional health status.  J. Pediatr. Orthop. 28, 199-212, 2008.

Wren TAL, Do KP, Hara R, Rethlefsen SA.  Use of a patella marker to improve tracking of dynamic hip rotation range of motion.  Gait and Posture 27, 530-534, 2008.

Wren TAL, Do KP, Hara R, Dorey FJ, Kay RM, Otsuka NY.  Gillette Gait Index as a gait analysis summary measure:  comparison with qualitative visual assessments of overall gait.  J. Pediatr. Orthop. 27, 765-768, 2007.

Wren TAL, Engsberg JR.  Normalizing lower extremity strength data for children without disability using allometric scaling.  Arch. Phys. Med. Rehab. 88, 1446-1451, 2007.

Wren TAL, Mitiguy PC.  A simple method to obtain consistent and clinically meaningful pelvic angles from Euler angles during gait analysis.  J. Appl. Biomech. 23, 218-223, 2007.

Wren TAL, Hara R, Sheng M, Otsuka NY, Bowen RE, Scaduto AA, Kay RM, Chan LS.  Agreement among three instruments for measuring functional health status and quality of life in pediatric orthopaedics.  J. Pediatr. Orthop. 27, 233-240, 2007.

Rethlefsen SA, Healy BS, Wren TAL, Skaggs DL, Kay RM.  Causes of in-toeing gait in children with cerebral palsy.  J. Bone Joint Surg. 88-A, 2175-2180, 2006.

Wren TAL, Do KP, Rethlefsen SA, Healy B. Cross-correlation as a method for comparing dynamic electromyography signals during gait.  J. Biomechanics 39, 2714-2718, 2006.

Wren TAL, Rethlefsen SA, Healy B, Do KP, Dennis S, Kay RM.  Reliability and validity of visual assessments of gait using a modified physician rating scale for crouch and foot contact.  J. Ped. Orthop. 25, 646-650, 2005.

Wren TAL, Woolf K, Kay RM.  How closely do surgeons follow gait analysis recommendations and why?  J. Ped. Orthop. B 14, 202-205, 2005.

Wren TAL, Rethlefsen SA, and Kay RM.  Prevalence of specific gait abnormalities in children with cerebral palsy:  Influence of cerebral palsy subtype, age, and previous surgery.  J. Ped. Orthop. 25, 79-83, 2005.

Kay RM, Rethlefsen SA, Fern-Bueno A, Wren TAL, Skaggs DL.  Botulinium toxin as an adjunct to serial casting treatment in children with cerebral palsy.  J. Bone Joint Surg. 86-A, 2377-2384, 2004.

Wren TAL, Do KP, Kay RM.  Gastrocnemius and soleus lengths in cerebral palsy equinus gait — differences between children with and without static contracture and effects of gastrocnemius recession.  J. Biomech. 37, 1321-1327, 2004.

Kay RM, Rethlefsen SA, Reed, M., Do KP, Skaggs DL, Wren TAL.  Changes in pelvic rotation after soft tissue and bony surgery in ambulatory children with cerebral palsy.  J. Ped. Orthop. 24, 278-82, 2004.

Kay RM, Rethlefsen SA, Ryan J, Wren TAL.  Outcome of gastrocnemius recession and tendo-achilles lengthening in ambulatory children with cerebral palsy.  J. Ped. Orthop. B 13: 92-98, 2004.

Kay RM, Rethlefsen SA, Kelly J, Wren TAL.  Predictive value of the Duncan-Ely test in distal rectus femoris transfer.  J. Ped. Orthop. 24: 59-62, 2004.


Bone

Wren TA, Chung SA, Dorey F, Bluml S, Adams GB, Gilsanz V.  Bone marrow fat is inversely related to cortical bone in young and old subjects.  J. Clin. Endocrin. Metabol. 96, 782-786, 2011.

Gilsanz V, Chalfant J, Kalkwarf H, Zemel B, Lappe J, Oberfield S, Shepherd J, Mahboubi S, Wren T, Winer K.  Age at onset of puberty predicts bone mass in young adulthood.  J Pediatrics 158, 52-57, 2011.

Di Iorgi N, Mo AO, Grimm K, Wren TAL, Gilsanz V.  Bone acquisition in healthy young females is reciprocally related to marrow adiposity.  J. Clin. Endocrin. Metabol. 95, 2977-2982, 2010.

Wren TAL, Gilsanz V.  The evolving role of imaging in the evaluation of bone structure.  J Bone Mineral Res. 24, 1943-1945, 2009.

Lee DC, Campbell P, Gilsanz V, Wren TAL.  Contribution of the vertebral posterior elements in AP DXA scans in young subjects.  J Bone Mineral Res. 24, 1398-1403, 2009.

Gilsanz V, Perez FJ, Campbell PP, Dorey FJ, Lee DC, Koh M, Wren TAL.  Quantitative computed tomography reference values for vertebral trabecular bone density in children and young adults.  Radiology 250, 222-227, 2009.

Lee DC, Gilsanz V, Wren TAL.  Limitations of pQCT metaphyseal bone density measurements.  J. Clin. Endocrin. Metabol. 92, 4248-4253, 2007.

Gilsanz V, Wren T.  Assessment of bone acquisition in childhood and adolescence.  Pediatrics 119(Suppl. 2), S145-149, 2007.

Wren TAL, Kim PS, Janicka A, Sanchez M, Gilsanz V.  Timing of peak bone mass:  discrepancies between CT and DXA.  J. Clin. Endocrin. Metabol. 92, 938-941, 2007.

Janica A, Wren TAL, Sanchez MM, Dorey F, Kim PS, Mittelman SD, Gilsanz V.  Fat mass is not beneficial to bone in adolescents and young adults.  J. Clin. Endocrin. Metabol. 92, 143-147, 2007.

Wren TAL, Gilsanz V.  Assessing bone mass in children and adolescents.  Current Osteoporosis Reports 4, 153-158, 2006.

Gilsanz V, Wren TAL, Sanchez M, Dorey F, Judex S, Rubin C.  Low level, high frequency mechanical signals enhance musculoskeletal development of young women with low BMD.  J. Bone Min. Res. 21. 1464-1474, 2006.

Wren TAL, Liu X, Pitukcheewanont P, Gilsanz V.  Bone densitometry in pediatric populations:  discrepancies in the diagnosis of osteoporosis by DXA and CT.  J. Pediatrics 146, 776-779, 2005.

Wren TAL, Liu X, Pitukcheewanont P, Gilsanz V.  Bone acquisition in healthy children and adolescents:  comparison of dual-energy x-ray absorptiometry and computed tomography measures.  J. Clin. Endocrin. Metabol. 90, 1925-1928, 2005.

Wren TAL, Yerby SA, Beaupré GS, and Carter DR.  Interpretation of calcaneus dual-energy x-ray absorptiometry measurements in the assessment of osteopenia and fracture risk.  Journal of Bone and Mineral Research 15, 1573-1578, 2000.


Tendon & Ligament

Loboa EG, Wren TAL, Beaupré GS, Carter DR.  Mechanobiology of soft skeletal tissue differentiation -- A fiber-reinforced poroelastic approach.   Biomechanics and Modeling in Mechanobiology 2, 83-96, 2003.

Wren TAL, Lindsey DP, Beaupré GS, Carter DR.  Effects of creep and cyclic loading on the mechanical properties and failure of human Achilles tendons.   Annals of Biomedical Engineering 31, 710-717, 2003.

Wren TAL.  A computational model for the adaptation of muscle and tendon length to average muscle length and minimum tendon strain.  Journal of Biomechanics 36, 1117-1124, 2003.

Wren TAL, Yerby SA, Beaupré GS, Carter DR.  Influence of bone mineral density, age, and strain rate on the failure mode of human Achilles tendons.  Clinical Biomechanics 16, 529-534, 2003.

Wren TAL, Yerby SA, Beaupré GS, Carter DR.  Mechanical properties of the human Achilles tendon.  Clinical Biomechanics 16, 245-251, 2003.

Wren TAL, Carter DR  Load and activity balance optimizes tendon/ligament healing.  BioMechanics November 2000 Supplement, 21-28, 2000.

Wren TAL, Beaupré GS, and Carter DR.  Mechanobiology of tendon adaptation to compressive loading through fibrocartilaginous metaplasia.  Journal of Rehabilitation Research and Development 37, 135-151, 2000.

Wren TAL, Beaupré GS, and Carter DR.  Tendon and ligament adaptation to exercise, immobilization, and remobilization.  Journal of Rehabilitation Research and Development 37, 217-224, 2000.

Wren TAL, Beaupré GS, and Carter DR.  A model for the loading-dependent growth, development, and adaptation of tendons and ligaments.  Journal of Biomechanics 31, 107-114, 1998.

Wren TAL and Carter DR.  A microstructural model for the tensile constitutive and failure behavior of soft skeletal connective tissues.  Journal of Biomechanical Engineering 120, 55-61, 1998.


Other

Glisanz V, Smith ML, Goodarzian F, Kim M, Wren TA, Hu HH.  Changes in brown adipose tissue in boys and girls during childhood and puberty.  J. Pediatrics, epub ahead of print, October 31, 2011.

Gilsanz V, Kremer A, Mo AO, Wren TAL, Kremer R.  Vitamin D status and its relation to muscle mass and muscle fat in young women.  J. Clin. Endocrin. Metabol. 95, 1595-1601, 2010.

Skaggs DL, Sankar WN, Albrektson J, Wren TAL, Campbell RM.  Weight gain following vertical expandable prosthetic titanium ribs surgery in children with thoracic insufficiency syndrome.  Spine 34, 2530-2533, 2009.

Wren TAL, Chen AY, Wang VJ, Claudius IA, Skaggs DL.  Prior treatment of fracture patients in a tertiary pediatric emergency department:  Informal referrals from other emergency departments.  J Pediatr. Orthop. 29, 137-141, 2009.

Gonzalez J, Wood JC, Dorey FJ, Wren TAL, Gilsanz V.  Reproducibility of carotid intima-media thickness in adolescents and young adults.  Radiology 247, 465-71, 2008.

Wren TAL, Bluml S, Tseng-Ong L, Gilsanz V.  Three-point technique of fat quantification of muscle tissue as a marker of disease progression in Duchenne muscular dystrophy:  preliminary study.  American Journal of Radiology 190, W8-W12, 2008.



Last modified November 10, 2011
Children's Hospital Los Angeles